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Right donor. Right sample. Right time.

At Research Donors, we connect researchers with high-quality biospecimens collected from healthy, fully consented donors. Our approach is built around getting you the right donor, the right sample, at the right time for your study. Whether that means tailoring to specific donor attributes, specifying collection protocols, or meeting tight delivery schedules, with rapid processing and responsive service, we help you generate reliable, reproducible results to support your research.

Explore our biospecimens

Right donor

Your research requires many carefully controlled inputs and some of the most important variables to consider are those that relate to the donors from whom biospecimens are collected.

Research Donors enable you to manage blood donor variability in the following ways:

Donor demographics

With a large, diverse community of over 3,000 healthy volunteer donors, we can collect samples that optimally match your requirements.

We routinely provide samples from specific donors, based on factors which are relevant to many biomedical research applications:

HLA and blood group
Previous viral infection history (including CMV and EBV)
Age (18-66), BMI, ethnicity and sex
Lifestyle factors including diet, nicotine and caffeine useage

Our recruitment process enables us in finding cohorts of donors that match your needs with a high level of control that small, local donor pools or national therapeutic collection services are unable to match.

This gives you to option to select and screen multiple donors for biomarkers of interest and subsequently recall specific donors for follow up collections of a variety of samples, from blood products through to leukopaks.

Donor health and screening

Common medications such as ibuprofen, antihistamines, steroids and vaccines can have significant impact on immune cell function which can affect research studies.

Our donors are healthy and medication free, and must meet our full eligibility criteria to donate. This includes exclusion if the donor has taken any prescription or over-the-counter medication in the past 7 days (except contraception), so you can be confident that samples from these donors can be used in your research studies without potential complications that can arise from the presence of pathologies or bioactive substances. In comparison, sourcing biospecimens from public collection organisations gives you no control over medication status.

Consent and ethics

Our service has been reviewed an approved by an NHS HRA Ethics Committee in the UK and Research Donors is licensed to collect and store biospecimens by the Human Tissue Authority.

Our consent form is optimised to ensure our donors are consenting for the full range of research applications, including genetic research and research involving the use of animals, among other uses. These uses are not typically covered by public blood donation services, which can be a major restriction of how samples can be used in the modern research environment.

Understanding our client needs, our consent form is also very clear that recipients of the samples may use them in commercial research and that all intellectual property rights to discoveries made using the samples are waived by donors. This robust consent process ensures maximum flexibility and clarity for our clients working in the biotechnology, diagnostics, medtech and pharmaceutical industries.

Our service relies on volunteer donors who are reimbursed a reasonable consideration for their time and inconvenience whilst attending their appointment. Donors are reimbursed on each occasion that they attend the clinic and participate in screening or donation. There is no different in the reimbursement paid to donors, regardless of the volume of blood that they donate.

A standard donation normally requires that the donor will be at the clinic for 1 hour to complete the screening and donation process. For this, donors are paid an inconvenience fee of £45. When specific donors are recruited for a study at a specified time, or asked to attend the clinic at a socially inconvenient time, they may receive a higher fee.

For apheresis collections, donors are required to attend significantly longer appointments – usually several hours. For this inconvenience, the fee is higher than for short whole blood donations.

Right sample

Our clinic has significant capacity to collect both whole blood and apheresis samples in a wide range of collection devices, giving you control over important factors such as collection tubes and sample format.

Our on-site blood processing laboratory enables rapid testing and processing of donations into a full range of biospecimen formats optimised to meet your research application requirements.

We undertake rapid viral testing of all donations prior to processing and release.

Blood biospecimen formats

We offer blood biospecimens in a wide range of collection devices, volumes and formats to ideally match your needs.

Whole blood is provided in bags or a wide range of anticoagulant and specialist collection tubes. Our specialist lab team also rapidly process whole blood to provide derivatives including plasma, serum, PBMCs and isolated immune cells.

Alongside our whole blood derived products, we collect leukopaks via apheresis using multiple Spectra Optia apheresis systems on site.

Our specialist service gives you greater control over how samples are collected to best suit your research study. Choose the collection device, processing times, storage and handling temperature, centrifugation parameters and more to ensure that samples fit in with your ideal protocol.

Sample type

Formats

Delivery*

Whole Blood

Sodium Heparin, Lithium Heparin, K2EDTA, K3EDTA, Sodium Citrate, Cell Free DNA, ACD-A Tubes

Fresh

CPD blood bags

Leukopaks

Full, half, quarter, tenth and 500 million cell formats from apheresis collection

Fresh or frozen

PBMCs

Produced from whole blood in any standard anticoagulant or isolated from leukapheresate.

Frozen formats
Leukapheresate (ACD) derived 25m & 250m cell format
Whole blood (CPD) derived 10m & 25m cell format.

Fresh or frozen

Buffy coat

Produced from whole blood collected in CPD bags or any standard anticoagulant tube 

Fresh 

Red Blood Cells 

Produced from whole blood collected in CPD bags or in any standard anticoagulant tube

Fresh

Leuko-reduced Red Blood Cells 

Produced from whole blood collected in CPD bags 

Fresh 

Plasma

Produced from whole blood collected in CPD bags or in any standard anticoagulant tube
Frozen stock sizes of 10, 25 and 100 ml.  

Fresh or frozen

Serum

Produced from whole blood collected in CAT (Clot Activator Tubes) tubes
Frozen stock sizes of 10, 25 and 100 ml.

Fresh or frozen

Isolated cells 

CD19+ B cells

Isolated from leukapheresate

Frozen

CD14+ Monocytes

CD56+ NK Cells

CD3+ Pan T Cells

CD4+ T Cells

CD8+ T Cells

*Delivery options are location dependent. Next day delivery available in UK and Europe. Same day is available in certain UK locations. Frozen samples can be shipped worldwide.

Sample processing and testing

Our sample processing and testing laboratory is directly connected to our blood donation clinic, enabling us to rapidly process and test blood samples ready for distribution.

We undertake a range of time critical blood, virology and cell analysis tests onsite.

All blood samples are tested for HIV, Hepatitis B&C, Syphilis and must be confirmed negative before progressing into laboratory processing and release to customers. Whilst researchers must always assume that blood samples may be infectious, our test-before-release policy gives your peace of mind that samples arriving in your lab have been tested for infectious agents.

Sample type

Processing 

Whole blood

Mixed during collection

Leukopaks

As per Spectra Optia MNC collection protocol. Manual splitting using a sterile closed system. Freezing in CryoStor CS10® and controlled rate freezing

PBMCs

Purified using density gradient centrifugation (Ficoll overlay) from whole blood or leukapheresate. Freezing in CryoStor® CS10 with controlled rate freezing

Serum

Serum is separated from whole blood by centrifugation after 30 minutes minimum clotting time and processed using manual sterile technique

Plasma

Plasma is separated from whole blood by centrifugation and processed using manual sterile technique

Red Blood Cells 

Separated from whole blood by centrifugation and processed using manual technique (tubes) or using an automated blood components separator (bags)

Leuko-reduced red blood cells

Whole blood collected with leukodepletion filter, RBCs separated from whole blood by centrifugation and processed using manual technique (tubes) or using an automated blood components separator (bags)

Buffy Coat

Separated from whole blood by centrifugation and processed using manual technique (tubes) or using an automated blood components separator (bags)

Isolated cells

Cells isolated via negative immunomagnetic separation technique from human leukapheresate collected in acid citrate dextrose, solution A (ACD-A).

 

Testing

Blood

Full Blood Count using Sysmex

Blood group & Rhesus Status

Virology

HIV, Hep B, Hep C,  Syphilis – serology for all donors (HIV, Hep B, Hep C by PCR for apheresis donors)

EBV/CMV for apheresis donors 

HTLV I & II for apheresis donors 

HLA typing

HLA-A, B, C, DRB1 –  4x high resolution typing by NGS

Cell viability

AOPI viability test using an automated cell counter 

Additional tests

qPCR for mycoplasma, bacteria & fungi for PBMCs, isolated cells & frozen leukopaks
Purity by flow cytometry for isolated cells
qPCR for COVID-19

Right time

We strive to ensure that our service matches your needs and priorities.

Our dedicated technical and customer service teams are on hand to help you determine the feasibility, costs and timelines needed to collect the samples you require for your research. With a large pool of donors and significant collection capacity, we can offer collections at short notice.

We work with trusted logistics partners to ensure delivery of biospecimens to your laboratory on time, ensuring the maximum viability and usability of samples we supply.

We work with knowledgable, local distribution partners who are also on hand to assist you with sourcing the best samples for your research.

How to order

We work with trusted distribution partners to provide researchers around the world with access to our blood biospecimens. Our partners have local technical and customer service teams who work closely with us to provide you with efficient local support to ensure the process is fast, straightforward, and that collections and deliveries are optimised to meet your needs.

Together we will work with you to;

Understand your requirements
We can discuss donor selection parameters, scheduling sample collection and agree on sample format and testing

Give you clear pricing
We will give you clear costings and work with your organisation’s procurement processes

Plan and organize delivery
We work together to prepare for the shipping and delivery of samples to your laboratory, knowing that on time delivery of your samples is of critical importance.

Fresh samples generally need to be ordered approximately 1 week in advance of delivery (exact timings to be confirmed).

Frozen stock samples can be selected and reserved via the Research Donors online stock system. This system gives you the flexibility to select and reserve your ideal frozen samples in our inventory, receive a quote from your local distributor and then place an order for the samples to be shipped to you.

We're ready to help

Whether you need more information about our donor collections or want to
discuss a custom request, our team is ready to assist.