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Human buffy coats

High-viability samples for your research

We provide high-quality fresh and frozen buffy coats from a diverse pool of healthy, consented donors. Each sample is processed promptly to preserve cell integrity and support a wide range of research applications.

High-yield buffy coats for immune cell isolation and analysis

High cell yield and purity

Processed promptly from healthy, fully consented donors, our buffy coats offer a rich source of white blood cells — ideal for immune cell isolation and downstream applications.

Customisable collection

Available from CPD whole blood bags or tubes with alternative anticoagulants to match your preferred protocols and research needs.

Reliable, rapid delivery

Shipped across Europe with next-day delivery, or same-day to select UK locations — ensuring optimal viability and performance on arrival.
Blood Products for Research
A Guide to the Right Anticoagulant for Blood Research

Learn how the choice of anticoagulants can impact your research

Read our blog

Explore the research applications

Immunology research

Investigate immune responses, cytokine production, cell signalling, and more

Haematology studies

Study blood disorders, haematopoiesis, and leukocyte function in greater detail

Blood Products for Research

Molecular biology

Extract DNA and RNA for genetic analysis and biomarker discovery

A Guide to the Right Anticoagulant for Blood Research

Flexible formats

Fresh buffy coats

 

Ideal for immediate use, these are collected and processed on-demand, with next-day delivery available across Europe and same-day options in select UK locations to ensure maximum cell viability.

Frozen buffy coats

 

Cryopreserved using CryoStor® CS10 and a controlled rate freezing system, these provide flexibility for future research use without compromising cell integrity.

What our customers say

"Research Donors have provided us with an excellent service. They have worked very closely with us to ensure that the products they supply are to the specifications that we require. The buffy coats that they provide are of a consistently high quality and the option of same day delivery is very valuable."

Senior ManagerAbzena, UK

"We’ve been using Research Donors and are very happy with their services. Samples are delivered on time and we always get a very quick response from the team. They are also very flexible and willing to discuss specific requests"

R&D ScientistNGS Company, Cambridge, UK

"In order to obtain good quality data, it is essential to work with fresh blood samples. In the past I have ordered such samples from many suppliers, and I have found Research Donors to be absolutely the best. They offer an extremely reliable overnight delivery, a very good customer service and, most importantly, a high-quality product. They are now my only supplier for human whole blood!"

Researcher in Fresh Blood Sample AnalysisEPFL, Switzerland

"We have been using Research Donors as our supplier of frozen human PBMC cells for over a year. The cells are always delivered promptly and arrive on the date specified at the time of ordering. Further, the viability of the cells are higher than what we have observed from alternative suppliers and the numbers of viable cells always exceeds the specification. Communication is fast, friendly, and informative and the staff were very willing to adapt the product to our needs."

Senior ScientistAnuCell Biosystems, Ireland

"We have used the Fresh Healthy Human Blood Service on several occasions and always received a helpful and efficient turnaround to our requests. The service has enabled timely access to good quality samples and facilitated effective development of our new generation products."

Scientista Life Science Company, Cardiff, UK

"We have purchased both frozen PBMCs and Human Plasma samples from multiple donors from Research Donors. They have always maintained excellent prompt communication throughout the whole process and the quality of products and cell viability has been consistently high. The customer service really excels, and the delivery service is great."

ScientistBiVictriX Therapeutics, Alderley Park, UK

"The blood service is always precise, and people are helpful. Samples are delivered in a timely manner and the quality of blood received from Research Donors is very high and I look forward to working with them again."

Senior Research AssociateKymab, UK

"They provided exactly what we needed, on time and to specification. Perhaps most importantly, they did what they said they would do and maintained fabulous communication throughout the ordering process. I would certainly recommend the service to others."

General ManagerComplement Genomics, UK

How to order

Browse our inventory

Access pre-collected, frozen biospecimens from our online catalogue

Browse available frozen samples
Register and add items to your basket
Submit your request to reserve samples
Your local distributor will follow up to confirm your order
Search stock inventory
Request a biospecimen collection
Design a custom collection based on your specific research needs
Specify your sample, donor & delivery criteria
Add to your quote request
Submit the request from your basket
Your local distributor will follow up to confirm your order

Request a biospecimen collection

Design a custom collection based on your specific research needs

1. Specify your sample, donor & delivery criteria

2. Add to your quote request

3. Submit the request from your basket

4. Your local distributor will follow up to confirm your order

What is a buffy coat?

The buffy coat is the fraction of an anticoagulated blood sample that contains most of the white blood cells and platelets, situated between the plasma and red blood cells after centrifugation. Comprising less than 1% of total blood volume, buffy coats are rich in white blood cells and platelets, essential for immunology and haematology research.

Learn more
Blood Products for Research
A Guide to the Right Anticoagulant for Blood Research

Right sample.
Right donor.
Right time.

If you can’t see exactly what you need, our team is ready to collaborate on custom collections designed to meet your specific requirements

Repeat donors for longitudinal studies

HLA-matched and tailored sample collections

Flexible volumes to support large-scale studies or specific applications

Let’s discuss how we can support your project

Ordering & delivery

We prioritise fast and reliable sample delivery to maintain cell viability

Same-day delivery options available in select UK locations

Standard next-day delivery across Europe

We're ready to help

Whether you need more information about our donor collections or want to
discuss a custom request, our team is ready to assist.