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Fresh & frozen PBMCs

High-quality PBMCs delivered with consistency

We provide fresh and frozen PBMCs from a diverse pool of healthy, HLA-typed donors. Each sample is processed and cryopreserved under strict quality control to ensure high viability and reliable performance.

High-quality PBMCs for immunology, oncology and beyond

Rapid isolation for optimal viability

PBMCs are processed and cryopreserved within 5 hours of donation using Ficoll overlay and CryoStor CS10® with controlled-rate freezing to ensure exceptional viability and functionality.

Comprehensive donor selection

Choose from a large inventory of ready-to-ship frozen PBMCs or request fresh or frozen samples from custom donor collections matched by HLA type, age, sex, and more.

Flexible sourcing options

Access large numbers of vials from a single donor or build diverse panels from multiple donors, ideal for high-throughput, consistent experimentation.

Accelerate discoveries

Immunology research

Study immune responses, vaccine development and autoimmune disorders

Haematology research

Investigate blood disorders and haematopoietic functions

Infectious disease

Understand host-pathogen interactions and disease mechanisms through the study of PBMCs

Flexible formats available to meet your needs

Fresh PBMCs

 

Isolated from whole blood or leukapheresis samples using Ficoll density gradient centrifugation, fresh PBMCs are processed on-demand and shipped under controlled conditions. 

Frozen PBMCs

 

Frozen within 5 hours of collection to preserve cell integrity, PBMCs are cryopreserved using CryoStor® CS10 and a controlled-rate freezing process. Ideal for flexible scheduling and long-term research without compromising recovery or performance.

Want to know why freezing methods matters?

Read why cryopreservation and controlled-rate freezing are critical for PBMC quality

Learn more

What our customers say

"We have been using Research Donors as our supplier of frozen human PBMC cells for over a year. The cells are always delivered promptly and arrive on the date specified at the time of ordering. Further, the viability of the cells are higher than what we have observed from alternative suppliers and the numbers of viable cells always exceeds the specification. Communication is fast, friendly, and informative and the staff were very willing to adapt the product to our needs."

Senior ScientistAnuCell Biosystems, Ireland

"We’ve been using Research Donors and are very happy with their services. Samples are delivered on time and we always get a very quick response from the team. They are also very flexible and willing to discuss specific requests"

R&D ScientistNGS Company, Cambridge, UK

"In order to obtain good quality data, it is essential to work with fresh blood samples. In the past I have ordered such samples from many suppliers, and I have found Research Donors to be absolutely the best. They offer an extremely reliable overnight delivery, a very good customer service and, most importantly, a high-quality product. They are now my only supplier for human whole blood!"

Researcher in Fresh Blood Sample AnalysisEPFL, Switzerland

"We have used the Fresh Healthy Human Blood Service on several occasions and always received a helpful and efficient turnaround to our requests. The service has enabled timely access to good quality samples and facilitated effective development of our new generation products."

Scientista Life Science Company, Cardiff, UK

"Research Donors have provided us with an excellent service. They have worked very closely with us to ensure that the products they supply are to the specifications that we require. The buffy coats that they provide are of a consistently high quality and the option of same day delivery is very valuable."

Senior ManagerAbzena, UK

"We have purchased both frozen PBMCs and Human Plasma samples from multiple donors from Research Donors. They have always maintained excellent prompt communication throughout the whole process and the quality of products and cell viability has been consistently high. The customer service really excels, and the delivery service is great."

ScientistBiVictriX Therapeutics, Alderley Park, UK

"The blood service is always precise, and people are helpful. Samples are delivered in a timely manner and the quality of blood received from Research Donors is very high and I look forward to working with them again."

Senior Research AssociateKymab, UK

"They provided exactly what we needed, on time and to specification. Perhaps most importantly, they did what they said they would do and maintained fabulous communication throughout the ordering process. I would certainly recommend the service to others."

General ManagerComplement Genomics, UK

How to order

Browse our inventory

Access pre-collected, frozen biospecimens from our online catalogue

1. Browse our frozen stock inventory
2. Add samples to your basket
3. Submit your request & reserve the samples
4. Your local distributor will be in touch to confirm

Request a biospecimen collection

Design a custom collection based on your specific research needs

1. Specify your sample, donor & delivery criteria
2. Add to your quote request
3. Submit the request from your basket
4. Your local distributor will be in touch to confirm

What are PBMCs?

Peripheral Blood Mononuclear Cells (PBMCs) are critical components of the immune system, comprising lymphocytes (T cells, B cells, NK cells) and monocytes. These cells play a crucial role in immunological research, vaccine development, and disease modelling.

Learn more

Right sample.
Right donor.
Right time.

If you can’t see exactly what you need, our team is ready to collaborate on custom collections designed to meet your specific requirements.

Repeat donors for longitudinal studies

HLA-matched and tailored sample collections

Flexible volumes to support large-scale studies or specific applications

Let’s discuss how we can support your project

Ordering & delivery

We prioritise fast and reliable delivery to maintain sample viability

Same-day delivery options available in select UK locations

Standard next-day delivery across Europe

We're here to help

Whether you need more information about our donor collections or want to
discuss a custom request, our team is ready to assist.